Frequently Asked Questions
No Question Too Big Or Too Small
Right now we can ship all of our product to all 50 states, expect for Topical Rapamycin and Low Dose Naltrexone. For Topical Rapamycin and Low Dose Naltrexone, our pharmacy’s license to ship is still pending in the following four states, though we do expect to have all licensing requirements updated in the near future. We currently cannot ship to the following: Arkansas. Alabama, Minnesota, and DC.
It takes two days for the pharmacy to process the medication and another two to three days for it to ship. Note that the pharmacy is closed on weekends, which can extend the processing and shipping times. When your order ships, you will receive a tracking link.
If you need to provide the Post Office with specific delivery instructions, please go to their website (usps.com) and click Quick Tools -> Track a Package. There is a section called “How do I leave delivery instructions.”
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After you complete your online health evaluation, a US-based physician will review your infor
mation and recommend a treatment plan. Once you approve your plan, we will ship your medication.
At Healthspan, we are committed to ensuring the effectiveness of the medications we prescribe. This commitment extends to addressing the challenges of bioavailability, which can notably impact the usage and efficiency of certain drugs, including rapamycin. To tackle this, we employ a robust testing program to select the formulations and brands of rapamycin that offer the best absorption levels.
Bioavailability is a key pharmacokinetic parameter that quantifies the percentage of the administered drug dose that successfully reaches systemic circulation and becomes available to exert its therapeutic effect. It’s a measure of the rate and extent of a drug’s absorption.
In assessing the bioavailability of our medications, we measure two critical pharmacokinetic parameters: Cmax and Tmax.
Cmax, or ‘maximum concentration,’ signifies the highest concentration a drug achieves in the body following administration and prior to the introduction of a second dose.
Tmax, or ‘time to maximum concentration,’ denotes the duration it takes for a drug to reach its Cmax post-administration, providing a measure of the drug’s absorption rate.
We believe in personalized care and thus, offer our patients the option to test their individual rapamycin levels. This enables us to understand each patient’s unique absorption profile of the medication, taking into account the variability of their biology. This approach ensures that our patients receive the most effective therapeutic regimen tailored to their individual needs.
We currently accept major credit cards such as Mastercard, Visa, and American Express. At the present time, we cannot accept HSA cards. pending in the following four states, though we do expect to have all licensing requirements updated in the near future. We currently cannot ship to the following: Arkansas. Alabama, Minnesota, and DC.
Once your doctor approves your plan, your card will be charged and your medication will be sent to the pharmacy to be filled and shipped. You will continue to be billed based on your subscription duration unless you make a change in your plan. Your prescription will be auto renewed based on your subscription duration.
You can cancel or pause your subscription at anytime by logging into your patient portal and navigating to your Subscriptions. For any additional questions, please message us in the application or email us at support@gethealthspan.com.
The Rapamycin Protocol is a fully comprehensive and personalized treatment plan guided by your Healthspan physician, medical team, and the Healthspan Research Review team.
Medical review by a US-based functional medicine doctor. Our US functional medicine doctors analyze your biomarkers and clinical data to prescribe personalized health recommendations. If your doctor deems the medication appropriate for you, you will be prescribed a treatment plan explaining the benefits and what to expect. Your doctor will review & optimize your dosage every 30 days.
Prescriptions delivered to your door. Our US-based pharmacies, which are LegitScript-certified, handle the direct shipment of your medication to your doorstep. We prioritize selecting medications with the highest bioavailability to maximize their effectiveness. Additionally, we provide patients with the option to test the concentrations of Sirolimus in their bloodstream, ensuring that the treatment is suitable and personalized for their specific needs.
Regular Lab Testing for continual optimization of your rapamycin protocol. We will optimize your dosing regimen by taking baseline blood draw to monitor biomarkers key to longevity and follow up with subsequent lab testing to see how your treatment is progressing and further optimize your treatment plan.
The Healthspan Research Review Team. Healthspan collaborates closely with esteemed researchers to conduct a meticulous meta-analysis of the most cutting-edge studies in the field of longevity medicine. This ensures that our protocol is based on the latest scientific findings. They are available to address any health-related inquiries you may have and offer an in-depth analysis of the most recent research pertaining to your specific concerns. This personalized approach allows us to provide you with tailored information and insights
Upon thorough medical review and screening, should you be deemed suitable for the Healthspan Rapamycin Protocol, your administration of Rapamycin will occur just once a week. For instance, should your current weekly dosage be 5mg, and you’re given 1mg pills, you’ll consume all five pills on a single day, as opposed to distributing them over the week. You’ll then rest until the next week.
The reason for this methodology stems from the cyclical nature of the benefits Rapamycin offers for anti-aging. Unlike transplant patients who take Rapamycin daily, the longevity benefits are drawn from the intermittent inhibition of mTOR. The therapeutic benefit of Rapamycin is derived from pulsated inhibition of mTOR, avoiding continuous inhibition. This approach prevents bloodstream concentrations of rapamycin that could inhibit mTOR-Complex 2, leading to immune suppression, which we aim to evade.
By adhering to a weekly dosage, adjusted according to your unique biomarkers and phenotype, we sidestep the immunosuppressive side effects of Rapamycin. We strive to administer Rapamycin in a manner that leverages the mTOR inhibitory benefits, such as stimulating autophagy, in cycles, and then returning to baseline mTOR activity.
At Healthspan, we harness the power of advanced technology and your unique biomarkers to craft a tailored Rapamycin dosage plan just for you. Typically, we initiate a patient’s treatment with a weekly dose of 3mg, carefully escalating this over time to reach the optimum dosage, which generally lies between 5 to 8mg per week. Please note, the provision of medication is strictly contingent upon a comprehensive medical review and initial screening process.
The risk of cancer is related to daily dosing for transplant patients, whereas our approach involves intermittent dosing every 7 days to avoid immune suppression. This distinction has varying implications for cancer. Rapamycin inhibits mTOR, exhibiting anti-cancer properties by preventing cell proliferation and inflammatory conditions conducive to cancer. Daily dosing may suppress the immune system, while our low-dose cyclical dosing enhances immune function, potentially contributing to rapamycin’s anti-cancer benefits. For more information about rapamycin, immune health, and cancer, please visit our Healthspan blog to access dedicated articles.
Topical supplements are applied to specific areas of the skin to deliver targeted and visible skin repair results. Healthspan’s topical rapamycin cell care formulation is designed to extend skin health by reducing cellular senescence in the skin layer.
Healthspan’s topical rapamycin is a unique skincare product that is formulated with the active ingredient rapamycin, a natural compound that has been shown to have anti-aging properties when applied topically to the skin. One key way Healthspan’s topical rapamycin differs from other topical supplements is that it targets the root causes of aging skin rather than just addressing the symptoms. This makes it different from other skincare products that might only offer short-term solutions and could potentially cause long-term damage to the skin.
Topical rapamycin offers a targeted approach to skin health, focusing directly on the cellular damage at the skin’s surface. This method effectively inhibits the accumulation of aged cells, leading to a rapid reduction in visible aging signs like wrinkles and loss of skin firmness—benefits that are more immediate compared to oral rapamycin. While oral rapamycin, typically prescribed by a doctor in capsule or tablet form, addresses systemic aging, topical rapamycin cream is specifically formulated to combat the aging process in the skin. reach the optimum dosage, which generally lies between 5 to 8mg per week. Please note, the provision of medication is strictly contingent upon a comprehensive medical review and initial screening process.
Yes, Healthspan’s topical rapamycin is safe for use when applied as directed. Our product is carefully formulated in US-based pharmacies that strictly adhere to all applicable federal laws and FDA regulations. This ensures high-quality standards and safety for our customers.
The most common negative side effect for first-time topical rapamycin users is dry skin. This is normally mild and lasts less than a week. For patients who experience discomfort, we recommend applying a chemical-free dermal hydration cream at night before bed.
Your Care Team
Our goal is always transparency, education, and empowerment of our patients. Have even more questions? Please reach out to our Care Team.
